Vitamin D is critical for the healthy growth and development of babies, toddlers, and children. It plays a vital role in calcium absorption, bone formation, immune system regulation, and overall health.
Adequate levels of vitamin D are required for maintaining bone strength, muscle health, and a robust immune system.
Without sufficient vitamin D, children are at risk for rickets, developmental issues related to skeletal growth, immune system dysfunction, and even impaired neurological development.
Vitamin D as a Hormone and its Systemic Influence
Vitamin D functions as a hormone that influences over 2,500 genes in the body, affecting a wide range of bodily functions, including cell growth, immune response, and inflammation control. Every cell in the human body has a vitamin D receptor, which highlights its widespread impact on health. Dr. Michael Holick, a pioneer in vitamin D research, has extensively documented how this hormone plays a crucial role in maintaining overall health. Deficiency in vitamin D has been linked to an increased risk of all-cause mortality, meaning that inadequate levels of this hormone can lead to a higher likelihood of dying from various health conditions. On the contrary, sufficient levels of vitamin D are associated with better all-cause longevity and improved health outcomes, including a 50% reduction in the risk of developing certain types of cancer.
Some Major Signs of Vitamin D Deficiency
Vitamin D deficiency in children and toddlers manifests through a wide variety of symptoms. Here are some key signs to watch out for:
Bone pain or tenderness: Especially in the legs, arms, or spine.
Delayed growth and development: Physical growth may be slower than expected.
Muscle weakness: Reduced strength or coordination.
Frequent illness: A compromised immune system can lead to more frequent infections and illnesses.
Restlessness and irritability: Deficiency can affect mood regulation and lead to behavioral issues.
Delayed tooth development: Vitamin D is critical for the development of tooth enamel and strength.
Rickets: This is a severe consequence of deficiency, leading to skeletal deformities, soft bones, and developmental delays.
Fatigue: Persistent tiredness that doesn't resolve with rest.
Allergies: Emerging research indicates a link between low vitamin D levels and a higher risk of developing allergies, including asthma.
Therapeutic Doses in Children
In Russia, therapeutic doses of vitamin D for children, particularly those up to 10 years old, can reach up to 4,000 IU daily under medical supervision to correct deficiencies. This is far above the preventive dose of 1,000–1,500 IU per day typically recommended for maintaining health. Therapeutic doses are essential when children show signs of deficiency or live in regions with low sunlight exposure, such as northern countries during the winter months.
Vitamin D Synthesis from Sun Exposure
For children living in equatorial regions, 20 minutes of sun exposure can result in the production of 4,000 to 10,000 IU of vitamin D. When exposed to one hour of daily sunlight, the amount produced can rise to 12,000 to 30,000 IU. This significant synthesis highlights the efficiency of vitamin D production in young skin under strong UV conditions.
By contrast, children living in northern regions—such as Russia, Scandinavia, or Canada—have limited UV exposure, especially during winter. These children rely more on supplementation to meet their vitamin D needs. Even at therapeutic doses of 4,000 IU daily, supplementation often cannot match the natural vitamin D production seen in children in equatorial regions.
The Disparity in Vitamin D Levels
The difference in vitamin D levels between children in northern regions and their equatorial counterparts is substantial. For instance, children in Russia might receive 1,000–1,500 IU daily through preventive supplementation, or up to 4,000 IU for therapeutic purposes. However, when compared to children in equatorial regions who can naturally produce up to 30,000 IU from one hour of sun exposure, these supplementation levels appear minimal. This disparity underscores the need for robust supplementation programs in northern regions during the winter months to ensure children's vitamin D levels are sufficient.
Darker-Skinned Children and Vitamin D Needs
Darker-skinned children in northern regions face additional challenges. Due to higher levels of melanin, which reduces the skin's ability to absorb UVB rays, they produce less vitamin D from sun exposure than lighter-skinned children. Darker-skinned individuals typically need five to ten times more sun exposure to produce the same amount of vitamin D In equatorial Africa, where children spend significant time outdoors, they can produce more than 30,000 IU of vitamin D daily through continuous sun exposure.
The Importance of Daily Vitamin D Exposure and Supplementation
The active hormonal form of vitamin D has a half-life of approximately 15 hours in the bloodstream, meaning that consistent, daily exposure or supplementation is crucial to maintain sufficient levels. Without regular intake, vitamin D levels can deplete rapidly, leading to deficiency. Given its role in regulating over 2,500 genes and every cell's vitamin D receptor, maintaining adequate levels is essential for overall health. Regular sun exposure and supplementation are critical, particularly in northern regions where sunlight is limited.
Northern Regions Needing Special Attention
Parents in the following northern regions should be particularly vigilant about their children's vitamin D levels during winter:
Scandinavia (Norway, Sweden, Finland), Russia, Canada, Northern United States, Northern Europe (UK, Iceland), North Korea and South Korea, Northern Japan
Vitamin D is crucial for children's growth, overall health, and disease prevention because it impacts every cell and system in the body. Children in equatorial regions naturally produce 12,000 to 30,000 IU of vitamin D from one hour of sun exposure. In contrast, children in northern regions produce much less and depend heavily on supplementation, especially during winter. Darker-skinned children need 5 to 10 times more sun exposure to produce the same levels of vitamin D due to higher melanin, making supplementation even more critical.
A child's need for vitamin D is greater than an adult's because of their rapid growth and development, which requires higher levels to support not only bone health but also immune function, neural development, and overall cellular health. Vitamin D influences over 2,500 genes and is linked to a lower risk of nearly every major disease, including cancer, autoimmune disorders, and cardiovascular conditions. Ensuring optimal vitamin D levels from childhood is fundamental to long-term health and longevity.
Given this, 4,000 IU daily should be considered a minimum baseline for children during months of low sun exposure in northern regions to ensure sufficient vitamin D for optimal growth, disease prevention, and cellular function.
Frontiers. Vitamin D Status in Russian Children and Adolescents: Contribution of Genetic and Exogenous Factors.
Michael Holick, PhD, MD. The Vitamin D Solution: A 3-Step Strategy to Cure Our Most Common Health Problems.
Public Health Recommendations in Finland. Finnish Institute for Health and Welfare: Vitamin D Recommendations.
Medical Research Links:
Scientific documentation of the relationship of vitamin D deficiency and the development of cancer. Journal of Environmental Pathology, Toxicology and Oncology
It is well known that vitamin D plays a key role in calcium homeostasis and is important for optimal skeletal growth. The major function of vitamin D is to enhance the efficiency of calcium absorption from the small intestine. Most physicians relate vitamin D deficiency to disorders of skeletal muscle. Vitamin D deficiency in children can manifest itself as rickets. In adults, vitamin D deficiency results in osteomalacia. Because most physicians do not appreciate the role of vitamin D deficiency in predisposing the development of cancer, we have written this important report as a wake-up call to physicians and other healthcare workers in documenting the relationship of vitamin D deficiency and cancer. Epidemiological data show an inverse relationship between vitamin D levels and breast cancer incidence. In addition, there is a well-documented association between vitamin D intake and the risk of breast cancer. Low vitamin D intake has also been indicated in colorectal carcinogenesis. A vitamin D deficiency has also been documented in patients with prostate cancer, ovarian cancer, as well as multiple myeloma. Larger randomized clinical trials should be undertaken in humans to establish the role of vitamin D supplementation in the prevention of these cancers.
Vitamin D3 is a secosteroid hormone produced in the skin in amounts estimated up to 25,000 international units (IUs) a day by the action of UVB radiation on 7-dehydrocholesterol. Vitamin D deficiency is common due to both lack of adequate sun exposure to the skin, and because vitamin D is present in very few food sources. Deficiency is strongly linked to increased risk for a multitude of diseases, several of which have historically been shown to improve dramatically with either adequate UVB exposure to the skin, or to oral or topical supplementation with vitamin D. In summary, long-term supplementation with vitamin D3 in doses ranging from 5000 to 50,000 IUs/day appears to be safe. There have been no cases of vitamin D3 induced hypercalcemia or any adverse events attributable to vitamin D3 supplementation in any patient.
Vitamin D and benign prostatic hyperplasia -- a review. The Canadian Journal of Urology
Introduction: Benign prostatic hyperplasia (BPH) is a more common form of lower urinary tract symptoms (LUTS). BPH is due to the excessive growth of both stromal and epithelial cells of the prostate. Fifty percent of men over the age of 50 will have this disease, along with the probability that 90% of men at the age of 80 will have an enlarged prostate. The prevalence of vitamin D deficiency in the male urological population may represent a connection between BPH and vitamin D.
Conclusion: The impact of vitamin D on prostate volume and BPH has shown promising results, thus proposing further studies on vitamin D and BPH be conducted.
Background: There is a need to develop and periodically evaluate new treatment strategies in major depression due to the high burden of non-response and inadequate response to antidepressants. Aim: We aimed to assess the effect of vitamin D supplementation on depression symptom scores among individuals with clinically diagnosed major depression.
Conclusion: Vitamin D supplementation favorably impacted depression ratings in major depression
Vitamin D alters developing neurons in the brain's dopamine circuit
Background: Neuroscientists have shown how vitamin D deficiency affects developing neurons in the brain's dopamine circuit, which may lead to the dopamine dysfunction seen in adults with schizophrenia.
Vitamin D supplementation during pregnancy may help prevent early developmental changes in dopamine neurons, potentially reducing the risk of Conclusion: Dopamine dysfunction and schizophrenia later in life.